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Winter 1997 Newsletter


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Antimicrobial Susceptibility Survey

1/97-10/97

 An antimicrobial susceptibility survey over time is an excellent way to monitor the development of resistant pathogenic bacteria. The following tables (Tables 1-3) summarize the antibiogram for pathogens isolated, during January to October of 1997, from swine (Table 1), bovine-dairy (Table 2) and bovine-beef (Table 3).

 "% S" indicates the percentage of organisms isolated from sick animals which were susceptible to the testing antibiotic(s) in vitro. Organisms with MS (moderately susceptible), I (intermediate) or R (resistant) are not included at this time. Therefore this data represents the most stringent susceptibility results. Please keep in mind that even though the in vitro data may not totally reflect the in vivo efficacy of an antibiotic, it remains the most reliable means to select for the best antibiotic(s) and the dose(s).

 As you are browsing through the table of interest, please keep in mind that the data did not account for moderately susceptible organisms. Therefore, one should not be overly concerned with the fact that 0% (N=300) of E. coli from pigs are susceptible to Tylosin. This is merely stating that all E. coli tested were not susceptible to tylosin at its lowest effective dose. Tylosin may be effective at a higher dose and only through the susceptibility data, and effective dose can be prescribed for efficient treatment.

Porcine Susceptibilities

1/97-10/97

 

Actinobacillus
sp.
Bordetella-
bronchiseptica
Escherichiasp.
Escher-i
chiahemolytic
Erysipelothrixrhu-
siopathiae
ANTIMICROBIC
#
%S
#
%S
#
%S
#
%S
#
%S
*Amikacin
16
100
53
100
301
99
91
99
9
22
Amox/Clava
11
91
39
46
180
36
53
49
2
50
*Ampicillin
16
63
53
11
301
40
91
52
9
11
Apramycin
16
44
52
29
300
67
91
62
9
11
*Cefitofur
16
94
53
2
300
97
91
96
9
100
Cephalothin
16
94
53
13
301
46
91
37
9
100
Clindamycin
6
17
17
0
126
0
39
0
8
75
Enrofloxacin
16
100
52
98
301
99
91
99
9
89
*Erythromycin
16
6
53
0
301
0
91
0
9
100
Florfenicol
5
100
14
7
120
3
38
5
4
75
*Gentamicin
16
100
53
100
301
71
91
64
9
33
*Lincomycin
10
0
36
0
175
0
52
0
1
100
Neomycin
16
75
52
100
300
44
91
54
9
33
Novobiocin
16
31
52
88
300
1
91
2
9
11
Oxacillin
16
44
53
17
301
3
91
3
9
100
*Penicillin
16
31
53
0
301
2
91
0
9
89
Sarafloxacin
5
80
14
7
120
95
38
95
4
100
*Sulfadiazine/T
11
55
38
5
179
2
53
2
2
0
Spectinomycin
16
6
52
2
300
12
91
27
9
89
Sulfachloropyr
16
94
52
12
300
26
91
27
9
33
*Tetracycline
16
44
53
98
301
2
91
3
9
22
*Tiamulin
16
63
52
0
300
28
91
24
9
89
Tilmicosin
16
75
52
10
300
2
91
2
9
78
Tribrissin
16
38
52
9
301
41
91
41
9
44
Tylosin
16
13
52
0
300
0
91
0
9

 

% S = % susceptible
* = FDA approved therapeutic agents for swine
Actinobacillus sp. - includes A. equuli, A. suis, and A. ureau.
Escherichia sp. - includes E. coli, lactose E. coli, and E. fergusonii.

Porcine Susceptibilities

1/97-10/97

 

Hemophilusparasuis Actinobacillus
pleuropnemonia
Klebsiella
pneumoniae
Pasteurella
sp.
ANTIMICROBIC
#
%S
#
%S
#
%S
#
%S
*Amikacin
25
84
82
56
19
100
215
99
Amox/Clava
17
59
98
9
89
142
95
*Ampicillin
25
92
82
77
19
0
215
95
Apramycin
25
56
82
7
19
89
215
35
*Cefitofur
25
96
82
99
19
100
215
97
Cephalothin
25
92
82
96
19
100
215
96
Clindamycin
11
91
27
7
10
0
82
1
Enrofloxacin
25
`100
82
100
19
100
215
100
*Erythromycin
25
92
82
10
19
0
215
1
Florfenicol
8
75
23
91
10
0
71
99
*Gentamicin
25
76
82
15
19
89
215
100
*Lincomycin
14
64
55
5
9
0
133
0
Neomycin
25
80
82
6
19
84
215
94
Novobiocin
25
96
82
11
19
0
215
96
Oxacillin
25
100
82
82
19
0
215
59
*Penicillin
25
68
82
56
19
0
215
60
Sarafloxacin
8
88
23
91
10
100
71
99
*Sulfadiazine/T
17
53
59
12
9
0
142
17
Spectinomycin
25
80
82
11
19
32
215
12
Sulfachloropyr
25
60
82
72
19
58
215
45
*Tetracycline
25
44
82
35
19
32
215
81
*Tiamulin
25
92
82
84
19
26
215
62
Tilmicosin
25
96
82
54
19
0
215
82
Tribrissin
25
48
82
33
19
53
215
39
Tylosin
25
96
82
20
19
0
215

 

% S = % susceptible

* = FDA approved therapeutic agents for swine
Actinobacillus pleuropnemoniae - includes types 1, 5, and 7.
Pasteurella sp. - includes P. aerogenes, P. haemolytica, and P. multocida.

 

Porcine Susceptibilities

1/97-10/97

 

 
Staphylococcus
aureus
Streptococcus
sp.
Staphylococcus
sp.
Salmonella
sp.
Streptococcus
suis
ANTIMICROBIC
#
%S
#
%S
#
%S
#
%S
#
%S
*Amikacin
13
100
42
52
26
96
96
100
197
67
Amox/Clava
3
100
23
100
10
10
59
47
152
100
*Ampicillin
13
8
42
52
26
77
96
53
197
69
Apramycin
13
100
42
31
26
100
96
81
197
35
*Cefitofur
13
100
42
100
26
96
96
100
197
100
Cephalothin
13
100
42
100
26
100
96
92
197
100
Clindamycin
10
20
19
58
16
38
41
0
55
27
Enrofloxacin
13
100
42
83
26
88
96
100
197
87
*Erythromycin
13
23
42
38
26
50
96
0
197
43
Florfenicol
10
0
18
17
16
0
34
0
43
14
*Gentamicin
13
100
42
24
26
92
96
84
197
60
*Lincomycin
3
0
23
4
10
40
53
0
142
26
Neomycin
13
100
42
43
26
96
96
60
197
39
Novobiocin
13
100
42
100
26
88
96
0
197
98
Oxacillin
13
100
42
100
26
96
96
0
197
99
*Penicillin
13
0
42
100
26
19
96
21
197
88
Sarafloxacin
10
50
18
22
16
25
34
100
43
5
*Sulfadiazine/T
3
33
23
9
10
70
59
0
152
7
Spectinomycin
13
0
42
60
26
0
96
0
197
64
Sulfachloropyr
13
77
42
38
26
77
96
17
197
18
*Tetracycline
13
8
42
3
26
31
96
15
197
4
*Tiamulin
13
100
42
60
26
73
96
29
197
88
Tilmicosin
13
31
42
57
26
54
96
3
197
30
Tribrissin
13
85
42
48
26
65
96
46
197
31
Tylosin
13
31
42
38
26
58
96
0
197

 

% S = % susceptible

* = FDA approved therapeutic agents for swine.
Streptococcus sp. - includes beta hemolytic, S. bovis, group C Strep., and non-hemolytic Strep.
Staphylococcus sp. - includes S. epidermidis and S. hyicus.
Salmonella sp. - includes groups C1, B, D, and E1.

 

Locations


ADDL-West Lafayette:
406 S. University
West Lafayette, IN 47907
Phone: 765-494-7440
Fax: 765-494-9181

ADDL-SIPAC
11367 E. Purdue Farm Road
Dubois, IN 47527
Phone: (812) 678-3401
Fax: (812) 678-3412

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